Rebuild Type 1 diabetes in one HTML file, from the whole body down to a single molecule.
THE BROKEN MESSAGE
Type 1 diabetes isn't caused by sugar, weight or lifestyle. It's autoimmune: the immune system destroys the beta cells in the pancreas that make insulin.
Those cells live in tiny clusters called islets, about 1–2% of the pancreas. After a meal, they sense rising glucose and release insulin. Insulin signals muscle and fat to take glucose in, and tells the liver to release less.
In Type 1, that signal disappears.
The fuel is still there. The message is missing.
So glucose builds up in the blood.
With almost no insulin, the body breaks down fat fast and the liver makes ketones. They can build up into diabetic ketoacidosis (DKA), a medical emergency.
Insulin therapy doesn't cure Type 1. It replaces a signal the body can no longer provide adequately, through injections or a pump. The daily challenge is balance: too little and glucose rises, too much and it can fall dangerously low. Food, exercise, stress and timing all change the picture.
Technology helps. A CGM tracks glucose every few minutes, and automated insulin delivery (AID) adjusts insulin based on those readings.
In the build, you can compare Healthy vs Type 1 vs Type 1 + insulin on the same meal, drag one slider from INTACT to BROKEN to watch the signal fade, follow a glucose molecule through the body, and explore CGM, pumps and AID.
Type 1 diabetes changes the system.
It doesn't define the person.
Built in Three.js. Educational visualization, not medical advice.
中文翻譯
用一個 HTML 文件重建 1 型糖尿病,從整個身體一直到單個分子。
壞掉的信息
1 型糖尿病不是由糖、體重或生活方式引起的。它是自身免疫性的:免疫系統摧毀了胰腺中製造胰島素的 β 細胞。
這些細胞生活在稱爲胰島的微小細胞團裏,約佔胰腺的 1–2%。餐後,它們感知到葡萄糖升高並釋放胰島素。胰島素向肌肉和脂肪發出信號,讓它們攝取葡萄糖,並告訴肝臟少釋放一些。
在 1 型糖尿病中,這個信號消失了。
燃料還在。信息卻不見了。
於是葡萄糖在血液中堆積。
由於幾乎沒有胰島素,身體會快速分解脂肪,肝臟產生酮體。酮體堆積可發展爲糖尿病酮症酸中毒(DKA),這是一種醫療急症。
胰島素治療不能治癒 1 型糖尿病。它通過注射或泵,替代身體已無法充分提供的信號。每天的挑戰是平衡:太少,葡萄糖會升高;太多,又可能危險地降得過低。食物、運動、壓力和時機都會改變局面。
技術能幫上忙。CGM 每隔幾分鐘追蹤一次葡萄糖,自動胰島素輸注(AID)根據這些讀數調整胰島素。
在這個作品裏,你可以比較同一餐下 Healthy vs Type 1 vs Type 1 + insulin,把一個滑塊從 INTACT 拖到 BROKEN,看信號逐漸消失,跟隨一個葡萄糖分子穿過身體,並探索 CGM、泵和 AID。
1 型糖尿病改變了系統。
它並不定義一個人。
用 Three.js 構建。教育性可視化,不構成醫療建議。