Rebuild Type 1 diabetes in one HTML file, from the whole body down to a single molecule.
THE BROKEN MESSAGE
Type 1 diabetes isn't caused by sugar, weight or lifestyle. It's autoimmune: the immune system destroys the beta cells in the pancreas that make insulin.
Those cells live in tiny clusters called islets, about 1–2% of the pancreas. After a meal, they sense rising glucose and release insulin. Insulin signals muscle and fat to take glucose in, and tells the liver to release less.
In Type 1, that signal disappears.
The fuel is still there. The message is missing.
So glucose builds up in the blood.
With almost no insulin, the body breaks down fat fast and the liver makes ketones. They can build up into diabetic ketoacidosis (DKA), a medical emergency.
Insulin therapy doesn't cure Type 1. It replaces a signal the body can no longer provide adequately, through injections or a pump. The daily challenge is balance: too little and glucose rises, too much and it can fall dangerously low. Food, exercise, stress and timing all change the picture.
Technology helps. A CGM tracks glucose every few minutes, and automated insulin delivery (AID) adjusts insulin based on those readings.
In the build, you can compare Healthy vs Type 1 vs Type 1 + insulin on the same meal, drag one slider from INTACT to BROKEN to watch the signal fade, follow a glucose molecule through the body, and explore CGM, pumps and AID.
Type 1 diabetes changes the system.
It doesn't define the person.
Built in Three.js. Educational visualization, not medical advice.
中文译文
用一个 HTML 文件重建 1 型糖尿病,从整个身体一直到单个分子。
坏掉的信息
1 型糖尿病不是由糖、体重或生活方式引起的。它是自身免疫性的:免疫系统摧毁了胰腺中制造胰岛素的 β 细胞。
这些细胞生活在称为胰岛的微小细胞团里,约占胰腺的 1–2%。餐后,它们感知到葡萄糖升高并释放胰岛素。胰岛素向肌肉和脂肪发出信号,让它们摄取葡萄糖,并告诉肝脏少释放一些。
在 1 型糖尿病中,这个信号消失了。
燃料还在。信息却不见了。
于是葡萄糖在血液中堆积。
由于几乎没有胰岛素,身体会快速分解脂肪,肝脏产生酮体。酮体堆积可发展为糖尿病酮症酸中毒(DKA),这是一种医疗急症。
胰岛素治疗不能治愈 1 型糖尿病。它通过注射或泵,替代身体已无法充分提供的信号。每天的挑战是平衡:太少,葡萄糖会升高;太多,又可能危险地降得过低。食物、运动、压力和时机都会改变局面。
技术能帮上忙。CGM 每隔几分钟追踪一次葡萄糖,自动胰岛素输注(AID)根据这些读数调整胰岛素。
在这个作品里,你可以比较同一餐下 Healthy vs Type 1 vs Type 1 + insulin,把一个滑块从 INTACT 拖到 BROKEN,看信号逐渐消失,跟随一个葡萄糖分子穿过身体,并探索 CGM、泵和 AID。
1 型糖尿病改变了系统。
它并不定义一个人。
用 Three.js 构建。教育性可视化,不构成医疗建议。